A man is shot and quickly buried in the high desert of west Texas. The body is found and reburied in Van Horn's town cemetery. Pete Perkins, a local ranch foreman, kidnaps a Border Patrolman and forces him to disinter the body. With his captive in tow and the body tied to a mule, Pete undertakes a dangerous and quixotic journey into Mexico.

Lauren, an impassioned American reporter for the Chicago Sentinel heads to Juarez, a Mexican bordertown, in order to investigate a series of mysterious slayings involving young factory women from all over Mexico. As she discovers hundreds of victims, she gains the trust of local factory workers but falls into danger.